The Financial Express

One in seven babies born with low birthweight worldwide: Study

| Updated: May 17, 2019 21:02:31

One in seven babies born with low birthweight worldwide: Study

More than 20 million babies were born with a low birthweight (less than 2500g; 5.5 pounds) in 2015—around one in seven of all births worldwide, according to a study.

Almost three-quarters of these babies were born in Southern Asia and sub-Saharan Africa, where data are most limited.

Progress is also slow in high-income countries including the UK, Finland, France, Germany, USA, Australia, and New Zealand.

The study authors call for international action to ensure that all babies are weighed at birth, to improve clinical care, and to promote public health action on the causes of low birthweight to reduce death and disability.

However, the problem also remains substantial in high-income countries in Europe, North America, and Australia and New Zealand, where there has been virtually no progress in reducing low birthweight rates since 2000, according to a new analysis undertaken by researchers from the London School of Hygiene & Tropical Medicine, UNICEF, and the World Health Organization (WHO), involving 148 countries and 281 million births, published in The Lancet Global Health journal.

In 2012, all 195 member states of the WHO committed to a 30 per cent reduction in low birthweight prevalence by 2025, compared with 2012 rates.

 The estimates, which are the first of their kind, found that worldwide low birthweight prevalence fell slightly from 17.5 per cent in 2000 (22.9 million low birthweight livebirths) to 14.6 per cent in 2015 (20.5 million).

However, the study indicates that at the current rate of progress—with a 1.2 per cent yearly decline in low birthweight rates between 2000 and 2015—the world will fall well short of the annual reduction rate of 2.7 per cent required to meet the WHO target of a 30 per cent reduction in prevalence between 2012 and 2025.

These findings highlight the urgent need for more investment and action to accelerate progress, through understanding and tackling key drivers of low birthweight throughout life—including extremes of maternal age, multiple pregnancy, obstetric complications, chronic maternal conditions (eg, hypertensive disorders of pregnancy), infections (eg, malaria), and nutritional status, as well as exposure to environmental factors such as indoor air pollution, and tobacco and drug use.

In low-income countries, poor growth in the womb is a major cause of low birthweight. In more developed regions, low birthweight is often associated with prematurity (a baby born earlier than 37 weeks gestation).

“Despite clear commitments, our estimates indicate that national governments are doing too little to reduce low birthweight, says lead author Dr Hannah Blencowe from the London School of Hygiene & Tropical Medicine, UK.

The lead author said “We have seen very little change over 15 years, even in high-income settings where low birthweight is often due to prematurity as a result of high maternal age, smoking, medically unnecessary caesarean sections and fertility treatments that increase the risk of multiple births. These are the underlying issues that governments in high-income countries should be tackling,”

Dr Hannah added  “To meet the global nutrition target of a 30% reduction in low birthweight by 2025 will require more than doubling the pace of progress.”

“Every newborn must be weighed, yet worldwide, we don’t have a record for the birthweight of nearly one third of all newborns,” says co-author Julia Krasevec, Statistics & Monitoring Specialist from UNICEF. “We cannot help babies born with low birthweight without improving the coverage and accuracy of the data we collect. With better weighing devices and stronger data systems, we can capture the true birthweight of every baby, including those born at home, and provide better quality of care to these newborns and their mothers.”

More than 80 per cent of the world’s 2.5 million newborns who die every year are low birthweight because they are either born preterm and/or small for gestational age.

Low birthweight babies who survive have a greater risk of stunting, and developmental and physical ill health later in life, including chronic conditions such as diabetes and cardiovascular disease.

In this study, the researchers performed a comprehensive search of the available data from national government databases and national surveys to estimate prevalence and track trends on low birthweight for livebirths in 148 countries from 2000 to 2015.

 In total, data were collated from over 281 million births. However, the authors note that 47 countries (including 40 low- and middle-income countries that account for almost quarter of all births worldwide) had insufficient data available.

One of the lowest rates of low birthweight in 2015 was estimated in Sweden (2.4  per cent). This compares to around 7 .0 per cent in some high-income countries including the USA (8.0 per cent), the UK (7.0 per cent), Australia (6.5 per cent), and New Zealand (5.7 per cent).  

The regions making the fastest progress are those with the highest numbers of low birthweight babies, Southern Asia and Sub-Saharan Africa, with a yearly decline in low birthweight prevalence of 1.4 per cent and 1.1 per cebt, respectively, between 2000 and 2015. 

Nevertheless, the overall number of low birthweight livebirths has actually increased in sub-Saharan Africa from 4.4 million to 5 million babies, largely due to demographic trends (such as fertility and migration). Similarly, Southern Asia still has almost half of the world’s low birthweight livebirths, with an estimated 9.8 million in 2015. 

High-income countries in North America, Europe, and Australia and New Zealand are some of the slowest progressing countries with an average reduction in prevalence of 0.01 per cent per year and a consistent rate of low birthweight of 7 per cent per year between 2000 and 2015 (table 4). 

Within these regions, Czechia (yearly increase 2 per cent), Ireland (1.3 per cent), Portugal (1.2 per ent), and Spain (1.1 per cent) are making the slowest progress, with an upward trend in low birthweight prevalence since 2000. 

Overall, the UK has experienced a downward trend in prevalence (yearly decline 0.3 per cent) since 2000, with total numbers fluctuating due to changes in livebirths each year (50,741 low birthweight livebirths in 2000 to 56,001 in 2015). 

“Low birthweight is a complex clinical entity composed of intrauterine growth restriction and preterm birth,” says co-author Dr Mercedes de Onis from WHO, Switzerland. 

The authors note several other limitations, including that the estimated trends are driven by changes in associated factors such as neonatal mortality and childhood undernutrition, which might not accurately reflect true changes in prevalence. 

Commenting on the implications of the findings, Professor Tanya Doherty from the South African Medical Research Council, South Africa, says: “The authors present an urgent and practical call to action to greatly improve the coverage of weighing at birth, including the need to count and weigh all babies (livebirths and stillbirths), strengthen existing data and health systems, and innovate better weighing devices. Yet achieving this practically, especially in emergency settings or weak health systems, remains a challenge.”



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